My sis. Is 20y she had a fever 40'c since five...

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Regarding your question,

Treatment of fever

It is common complaint due to many factors and causes. Evaluation and treatment of like condition is by the following

• At first, your sister can take antipyretic drug like PARACETAMOL 500 mg many times daily to decrease and relieve fever
• It may related to many medical causes varied from viral infections to other diseases.
• Seek your medical help for clinical examination
• Your sister has to do investigations to clarify cause of fever

Causes of fever

There are many causes like

• URTIs
• Viral infections
• Urinary tract infections
• Brain infections
• Immune diseases
• Others

Investigations to do

You can do the following

• CBC
• Urine analysis
• Stool analysis
• ESR
• CRP
• ANA

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Kind Regards