Can erection of the penis for one hour cause the...

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Regarding your question,

Can prolonged sex cause penis fatigue

There is capacity for penis and for sexual activity thus based on your question the answer  yes. prolonged sex and prolonged erection cause fatigue of penis thus it is better to do the following

• Avoid stress and depression as you can
• Eat more healthy foods like fruits and vegetables.
• Exercise daily for at least 30 minutes to enhance body ability.
• Stop smoking and alcohol consumption.
• Rest between every sexual intercourse to rest your penis.

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